Anti-BCL6 Polyclonal Antibody
产品名称: Anti-BCL6 Polyclonal Antibody
英文名称: BCL5;BCL6A;LAZ3;ZBTB27;ZNF51
产品编号: K005059P
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: WB IF
北京索莱宝科技有限公司--实验室产品
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The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.