Anti-Cyclin D2 Monoclonal Antibody
产品名称: Anti-Cyclin D2 Monoclonal Antibody
英文名称: KIAK0002;MPPH3
产品编号: K001385M
产品价格: null
产品产地: 北京
品牌商标: Solarbio
更新时间: null
使用范围: WB
北京索莱宝科技有限公司--实验室产品
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The protein encoded by this gene belongs to the highly conserved cyclin family,whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle.Cyclins function as regulators of CDK kinases.Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event.This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition.This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb.Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation.High level expression of this gene was observed in ovarian and testicular tumors.[provided by RefSeq,Oct 2008]