Anti-PTBP1 Polyclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司--实验室产品
Anti-PTBP1 Polyclonal Antibody

Anti-PTBP1 Polyclonal Antibody

商家询价

产品名称: Anti-PTBP1 Polyclonal Antibody

英文名称: HNRNP-I;HNRNPI;HNRPI;PTB;PTB-1;PTB-T;PTB2;PTB3;PTB4;pPTB

产品编号: K000419P

产品价格: null

产品产地: 北京

品牌商标: Solarbio

更新时间: null

使用范围: WB IHC IF

北京索莱宝科技有限公司--实验室产品
  • 联系人 :
  • 地址 : 北京市通州区马驹桥联东U谷景盛南四街85A三层
  • 邮编 :
  • 所在区域 : 北京
  • 电话 : 010-563*1250 点击查看
  • 传真 : 点击查看
  • 邮箱 : 2748554845@qq.com

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.