Uniprot ID:Q14011
Species Reactivity:Human
Antibody type:Polyclonal Antibody
Aliases:A18 hnRNP,Glycine-rich RNA-binding protein CIRP,CIRBP,A18HNRNP, CIRP,Raised in:Rabbit
Background\Function :Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
Stroage Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purity:Antigen Affinity Purified
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