NBN monoclonal antibody (M02), clone 2C7
产品名称: NBN monoclonal antibody (M02), clone 2C7
英文名称: NBN monoclonal antibody (M02), clone 2C7
产品编号: H00004683-M02
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
                            亚诺法生技股份有限公司(Abnova)
                            
                                
                            
                        
                    - 联系人 :
 - 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
 - 邮编 : 11493
 - 所在区域 : 台湾
 - 电话 : +886-920**1152 点击查看
 - 传真 : 点击查看
 - 邮箱 : sales@abnova.com.tw
 
- Specification
 
- Product Description:
 - Mouse monoclonal antibody raised against a partial recombinant NBN.
 
- Immunogen:
 - NBN (NP_002476, 645 a.a. ~ 754 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
 
- Sequence:
 - DDSEMLPKKLLLTEFRSLVIKNSTSRNPSGINDDYGQLKNFKKFKKVTYPGAGKLPHIIGGSDLIAHHARKNTELEEWLRQEMEVQNQHAKEESLADDLFRYNPYLKRRR
 
- Host:
 - Mouse
 
- Reactivity:
 - Human
 
- Isotype:
 - IgG2a Kappa
 
- Storage Buffer:
 - In 1x PBS, pH 7.2
 
- Storage Instruction:
 - Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
 
- Quality Control Testing:
 - Antibody Reactive Against Recombinant Protein.

Western Blot detection against Immunogen (37.84 KDa) . 
- MSDS:
 
Download
- Applications
 
- Western Blot (Recombinant protein)
 - Protocol Download
 
- Sandwich ELISA (Recombinant protein)
 
- Detection limit for recombinant GST tagged NBN is 0.3 ng/ml as a capture antibody.
 - Protocol Download
 
- Application Image
 
- Western Blot (Recombinant protein)
 
- Sandwich ELISA (Recombinant protein)
 
- enlarge
 
- ELISA
 
- Entrez GeneID:
 - 4683
 
- GeneBank Accession#:
 - NM_002485
 
- Protein Accession#:
 - NP_002476
 
- Gene Name:
 - NBN
 
- Gene Alias:
 - AT-V1,AT-V2,ATV,FLJ10155,MGC87362,NBS,NBS1,P95
 
- Gene Description:
 - nibrin
 
- Gene Ontology:
 - Hyperlink
 
- Gene Summary:
 - Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq
 
- Other Designations:
 - Nijmegen breakage syndrome 1 (nibrin),cell cycle regulatory protein p95,p95 protein of the MRE11/RAD50 complex
 
- Gene Pathway
 
- Related Disease
 
- Acute Disease
 - Adenocarcinoma
 - Astrocytoma
 - Ataxia telangiectasia
 - Brain Neoplasms
 - Breast cancer
 - Breast Neoplasms
 - Carcinoma, Basal Cell
 - Carcinoma, Ductal
 - Carcinoma, Ductal, Breast
 - Carcinoma, Non-Small-Cell Lung
 - Carcinoma, Transitional Cell
 - Central Nervous System Neoplasms
 - Chromosomal Instability
 - Chromosome Aberrations
 - Chromosome Breakage
 - Chromosome Deletion
 - Cleft Lip
 - Cleft Palate
 
